Matthias Gromeier, MD



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Professor of Neurosurgery
Professor in Molecular Genetics and Microbiology
Professor in Medicine
Department / Division:
Neurosurgery / Neurosurgery
Research Drive
Rm 401D MSRB1
Durham, NC 27710
Office Telephone:
(919) 668-6205
  • MD, University of Hamburg (Germany), 1992
  • Postdoctoral fellow, Molecular Genetics & Microbiology, State University of New York at Stony Brook
Research Interests:
Protein Synthesis Regulation
Signal Transduction
Growth & Proliferation Control in Cancer
Oncolytic Viruses
Viral Neuropathogenesis
Immunization Vectors
Representative Publications:
  • Dobrikov, M; Dobrikova, E; Shveygert, M; Gromeier, M. Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1. Molecular and Cellular Biology. 2011;31:2947-2959.  Abstract
  • Wang, ES; Dobrikova, E; Goetz, C; Dufresne, AT; Gromeier, M. Adaptation of an ICAM-1-tropic enterovirus to the mouse respiratory tract. Journal of virology. 2011;85:5606-5617.  Abstract
  • Goetz, C; Everson, RG; Zhang, LC; Gromeier, M. MAPK signal-integrating kinase controls cap-independent translation and cell type-specific cytotoxicity of an oncolytic poliovirus. Molecular Therapy. 2010;18:1937-1946.  Abstract
  • Shveygert, M; Kaiser, C; Bradrick, SS; Gromeier, M. Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction. Molecular and Cellular Biology. 2010;30:5160-5167.  Abstract
  • Walters, RW; Bradrick, SS; Gromeier, M. Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression. RNA (New York, N.Y.). 2010;16:239-250.  Abstract